Kinetics of creatine kinase in different protocols training: clinical study

Abstract

Objective: To analyze the kinetics of plasma creatine kinase concentration in serial blood collections before and after application of a resistance training protocol with emphasis on the different muscular actions: concentric, eccentric and isometric. Materials and methods: This is a clinical study in which 10 male individuals aged 18 to 25 were physically active. All of them performed the three muscular action protocols distributed in three stages: Step 1 (concentric); Step 2 (eccentric) and Step 3 (isometric). Before performing the experimental procedures, a stage of ambientization and correction of the exercises was performed, after which the Maximum Repetition Test (MR) was performed to determine the intensity of the training. During the experimental procedures blood samples (5ml) were collect- ed 30 minutes before and (5ml) immediately after the protocol was performed. Results: The results did not show statistical significance (p <0.05) between the different types of muscular contractions. Basal concentric total CK values of 769.2 ± 1406.9 and post-training of 981.2 ± 1659.9 were obtained; basal eccentric of 398.5 ± 306.2 and post-training of 533.4 ± 344.0; isometric baseline of 3477.5 ± 3440.8 and post-training 3668.7 ± 3592.0. Already the CK-MB values of baseline concentric was of 25.9 ± 14.31 and post workout of 25.4 ± 13.05; basal eccentric 17.1 ± 8.96 and post-training 20.5 ± 9.72; baseline isometric 43 ± 27.49 and post-training 47 ± 30.15. Conclusion: There is no significant difference between the different types of muscle contraction in CK kinetics. However, it is important to note that, even though there is no statistical increase in plasma concentrations of CK and CK-MB, there is a tendency to increase these parameters in all muscular actions.